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The title compound N-(2-(1-butyl-3-phenylureido)-1H-indol-3-yl)-N-(4-chloro- phenyl)- benzamide (C_(32)H_(29)ClN_4O_2, M_r = 537.04) was synthesized by a sequential Ugi four com- ponent condensation (4CC)/aza-Wittig/carbodiimide-mediated cyclization, and the structure was characterized by NMR, IR, MS, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belongs to orthorhombic, space group P2_12_12_1 with a = 11.3663(9), b = 13.3248(10), c = 18.7887(15), V = 2845.6(4)~3, Z = 4, D_c = 1.254 mg/m3, μ = 0.170 mm~(-1), F(000) = 1128, the final R = 0.0538 and wR = 0.1187. X-ray analysis reveals that the new five-membered ring (C(14)-C(15)-N(2)-C(16)-C(21)) and the benzene ring (C(16)-C(21)) are nearly coplanar.
The title compound N- (4-chloro- phenyl) -benzamide (C_ (32) H_ (29) ClN_4O_2, M_r = 537.04) was synthesized by a sequential Ugi four-member condensation (4CC) / aza-Wittig / carbodiimide-mediated cyclization, and the structure was derived by NMR, IR, MS, elemental analysis and X-ray single-crystal diffraction analysis . The crystal belongs to orthorhombic, space group P2_12_12_1 with a = 11.3663 (9), b = 13.3248 (10), c = 18.7887 (15) , V = 2845.6 (4) ~ 3, Z = 4, D_c = 1.254 μ = 0.170 mm -1, F (000) = 1128, the final R = 0.0538 and wR = 0.1187. X-ray analysis reveals that the new five- membered ring (C (15) -N (2) -C (16) -C (21)) and the benzene ring (C (16) -C (21)) are nearly coplanar.