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目的观察初治鼻咽癌调强放疗和常规放疗的急性不良反应,比较两组的差异。方法将60例初治鼻咽癌患者分为常规放疗组(33例)和调强放疗组(27例),观察放疗中患者的急性皮肤反应,口干,口咽黏膜炎,急性腮腺肿胀等急性不良反应。结果调强放疗组患者的急性皮肤反应,口干和急性腮腺水肿等急性不良反应明显低于常规放疗组,对口腔黏膜炎调强放疗并无优势。结论采用调强放射治疗可以减轻患者的皮肤反应,口干,急性腮腺水肿等早期不良反应。
Objective To observe the acute adverse reactions of initial radiotherapy and conventional radiotherapy of nasopharyngeal carcinoma, and to compare the differences between the two groups. Methods Sixty patients with newly diagnosed nasopharyngeal carcinoma were divided into conventional radiotherapy group (n = 33) and intensity modulated radiotherapy group (n = 27) .Acute dermal reactions, dry mouth, oropharyngeal mucositis, acute parotid gland swelling, etc. were observed during radiotherapy Acute adverse reactions. Results Acute adverse reactions such as acute skin reaction, dry mouth and acute parotid edema in IMRT group were significantly lower than those in conventional radiotherapy group. There was no advantage in IMRT with radiotherapy. Conclusions IMRT can reduce the early side effects such as skin reaction, dry mouth and acute parotid edema.