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目的运用强化措施对住院肝癌患者进行干预,了解其对继发肺部感染的发生率、患者满意度和生活质量评分的影响,为预防肝癌患者继发肺部感染提供一定的理论依据。方法选择2010年8月-2012年8月住院的80例行肝动脉化疗栓塞术(TACE)治疗且中性粒细胞≤10×109/L肝癌患者,将其随机分为强化组和对照组,每组40例;对照组术后行常规化疗措施及健康教育指导,强化组在此基础上给予强化肺部干预措施;分别对两组患者继发肺部感染的发生率、患者满意度、生活质量评分进行比较分析。结果肝癌患者化疗后肺部感染率强化组为7.5%、对照组为27.5%,经χ2检验,强化组肺部感染率低于对照组,差异有统计学意义(χ2=5.541,P<0.05);患者满意度强化组为82.5%,对照组为25.0%,两组比较差异有统计学意义(χ2=27.195,P<0.01);强化组的总生存质量评分、食欲、睡眠、自理能力、心理能力、对疾病的认识评分明显高于对照组,差异均有统计学意义(P<0.01)。结论强化干预措施能够降低肝癌患者化疗期继发肺部感染的发生率和增加患者满意度,增强了患者化疗期间的抵抗力,从而在提高了患者的生活质量。
Objective To evaluate the effect of intensive treatment on hospitalized patients with hepatocellular carcinoma (HCC) to understand their influence on the incidence of secondary pulmonary infection, patient satisfaction and quality of life scores, and to provide some theoretical basis for prevention of secondary pulmonary infection in patients with liver cancer. Methods Eighty patients with hepatocellular carcinoma who underwent transcatheter arterial chemoembolization (TACE) and ≤10 × 109 / L neutrophils were selected from August 2010 to August 2012 and were randomly divided into the intensive group and the control group. Each group of 40 cases; control group after conventional chemotherapy and health education guidance, intensive group on the basis of this to give intensive lung intervention; respectively, two groups of patients with secondary pulmonary infection incidence, patient satisfaction, life Quality scores for comparative analysis. Results The rates of lung infection in patients with hepatocellular carcinoma after chemotherapy were 7.5% in the intensive group and 27.5% in the control group. The χ2 test showed that the lung infection rate in the intensive group was lower than that in the control group (χ2 = 5.541, P <0.05) ; The satisfaction degree of patients in intensive group was 82.5% and in control group was 25.0%, the difference between the two groups was statistically significant (χ2 = 27.195, P <0.01); the scores of total quality of life, appetite, sleep, self-care ability, Ability, awareness of the disease score was significantly higher than the control group, the difference was statistically significant (P <0.01). Conclusion Intensive intervention can reduce the incidence of secondary pulmonary infection during chemotherapy, increase patient satisfaction and increase the resistance of patients during chemotherapy, thus improving the quality of life of patients with liver cancer.