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目的:评价限制性液体复苏在肝硬化合并上消化道大出血休克中的治疗效果.方法:56例肝硬化合并上消化道大出血休克患者随机分为观察组(限制性液体复苏组)和对照组(积极液体复苏组).分别对两组患者复苏后血乳酸、血气碱剩余值,24h及72h药物止血率进行统计学分析.结果:观察组在复苏后血乳酸、血气碱剩余值、24h药物止血率优于对照组,差异有统计学意义(P0.05).结论:限制性液体复苏可改善组织的有效灌注和氧供,早期控制肝硬化合并上消化道大出血,值得临床推广.“,”Objective To evaluate the effect of limited fluid resuscitation in the treatment of cirrhosis patients with upper gastrointestinal bleeding and hypovolemic shock.Methods 56 cirrhosis patients with upper gastrointestinal bleeding and hypovolemic shock were randomly devided into the observation group(limited fluid resuscitation group) and the control group(aggressive fluid resuscitation group).After fluid resuscitation,the blood lactate,base excess values(BE),the drug haemostatic rates in 24h and 72h were analyzed and compared between the two groups.Results Compared with those of the control group,the blood lactate,base excess values(BE) and the drug haemostatic rate in 24h of the observation group were significantly superior(P0.05).Conclusion Limited fluid resuscitation can maintain effective perfusion and oxygen supply to the vital organs,and showes advantage for cirrhosis patients with upper gastrointestinal bleeding and hypovolemic shock.