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观察５９例维持性血液透析（ＭＨＤ）、３６例持续性非卧床性腹膜透析（ＣＡＰＤ）病者透析前后血脂、脂蛋白及载脂蛋白的变化。结果显示，ＭＨＤ病者透析后血甘油三脂（ＴＧ）、极低密度脂蛋白胆固醇（ＶＬＤＬ－Ｃ）轻度升高，载脂蛋白Ｂ－１００（ａｐｏＢ－１００）明显升高，总胆固醇（ＴＣ）、ａｐｏＡＩ、ａｐｏＡⅡ、ａｐｏＣⅡ及ａｐｏＣⅡ／ａｐｏＣⅢ均明显降低；ＣＡＰＤ病者治疗后ＴＧ、低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）、ＶＬＤＬ－Ｃ、ａｐｏＢ－１００、ａｐｏＣⅢ较透析治疗前明显升高，而ａｐｏＡⅠ明显降低；有动脉硬化合并症的透析患者，其脂质代谢紊乱明显重于无动脉硬化的患者。上述事实表明，透析病者有明显的脂质代谢紊乱，ＣＨＤ和ＣＡＰＤ对透析病者脂质代谢的影响有不同，且两者均存在加速和对抗动脉硬化因子的失衡，有明显的促进动脉硬化的倾向。
The changes of blood lipids, lipoproteins and apolipoproteins in 59 patients with maintenance hemodialysis (MHD) and 36 patients with persistent ambulatory peritoneal dialysis (CAPD) before and after dialysis were observed. The results showed that the levels of triglyceride (TG) and very-low density lipoprotein cholesterol (VLDL-C) in patients with MHD increased slightly, the levels of apoB-100 and apoB- TC, apoAI, apoAⅡ, apoCⅡand apoCⅡ / apoCⅢwere significantly lower in CAPD patients than in those before CAPD treatment. The levels of TG, low density lipoprotein cholesterol (LDL-C), VLDL- , While apoA Ⅰ significantly reduced; patients with arteriosclerotic complications of dialysis patients, the lipid metabolism was significantly heavier than patients without atherosclerosis. The above facts show that dialysis patients have obvious lipid metabolism disorders, CHD and CAPD on dialysis patients with lipid metabolism are different, and both exist accelerated and antagonistic imbalance of atherosclerosis, and significantly promote atherosclerosis Propensity.