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本文报道242例高脂血症患者血小板(PLT)、平均血小板数(MPLT)及平均血小板体积(MPV)等参数的测定结果,其中高胆固醇并高甘油三酯患者,PLT、MPLT及巨大血小板比例(Macro-PLT)高于正常,MPV正常;而单纯高胆固醇或高甘油三酯患者,上述指标与正常人无显著性差异。提示高胆固醇并高甘油三酯患者,存在血小板生成动力学异常,其血小板的破坏增加,生成率加速、但处于一种高水平的动态平衡之中。这可能是高脂血症出现高凝状态的原因之一。同时表明此类患者使用抗血小板疗法具有一定的合理性和必要性。
This paper reports the determination of platelet (PLT), mean platelet count (MPLT) and mean platelet volume (MPV) in 242 patients with hyperlipidemia. The patients with hypercholesterolemia and hypertriglyceridemia, PLT, MPLT, (Macro-PLT) higher than normal, MPV normal; and simple hypercholesteremia or hypertriglyceridemia patients, the above indicators and normal no significant difference. Prompted high cholesterol and high triglyceride patients, there is an abnormal platelet production kinetics, the increase of its destruction of platelets, the acceleration rate, but in a high level of dynamic balance. This may be one of the reasons hypercoagulable hypercoagulable state. At the same time shows that such patients with antiplatelet therapy has some rationality and necessity.