骨肉瘤多见于长骨干骺端,文献中尚未见原发于脑实质内者。本文报告一例原发于脑实质内的骨肉瘤,并略加讨论。患者女,22岁。8年来经常发作性头部钝痛,无发烧、呕吐等。当地医院诊为“神经性头痛”,服止痛、调节脑神经等药物,效果不佳。头痛每在“感冒”或“劳累”后发作,持续数日或十数日缓解。近半月头痛加重,剧烈时伴恶心及非喷射性呕 Osteosarcoma more common in long bone metaphysis, the literature has not yet seen in the parenchyma of the brain. This article reports a case of osteosarcoma that originates in the parenchyma of the brain and is briefly discussed. Female patient, 22 years old. 8 years often episodes of head dull pain, no fever, vomiting and so on. The local hospital diagnosed as “neurological headache”, serving painkillers, regulating the brain and other drugs, the effect is not good. Every time a headache occurs after a “cold” or “tiredness”, it lasts for days or ten days to ease. Half a month aggravated headache, severe nausea and non-jet nausea