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目的探讨重度子痫前期不同发病孕周与围产儿结局的关系。方法对我院112例重度子痫前期患者以孕34周发病时间为界,分为早发型和晚发型两组,即A组孕妇55例,新生儿59例,B组孕妇57例,新生儿62例,对两组孕妇及分娩新生儿的一般临床资料,新生儿疾病的发生情况及围产结局进行分析比较。结果(1)两组孕妇分娩孕周及早产发生率的比较,有显著统计学差异(P(0.01)。(2)两组新生儿出生时的平均胎龄、平均出生体重、平均身长进行统计学比较,有显著差异(P(0.01)。A组新生儿中低出生体重儿41例(发生率69.49%),B组17例(发生率27.42%),两组统计学比较有显著差异(P(0.01)。A组中小于胎龄儿(SGA)11例(18.64%),适于胎龄儿(AGA)46例(77.97%),大于胎龄儿(LGA)2例(3.39%),B组新生儿中SGA14例(22.58%),AGA40例(65.57%),LGA8例(12.90%),两组比较,差异无统计学意义(P>0.05)。(3)两组新生儿先天畸形,新生儿窒息,呼吸系统疾病,酸中毒及糖代谢混乱的发病率比较,均有统计学差异(P(0.05)。其他各种疾病的发病率比较,无统计学意义。(4)比较两组孕妇妊娠不良结局的发生率,则早发型组为6例,晚发型组为0,两组比较有统计学差异(P值为0.012)。结论重度子痫前期患者的发病孕周直接影响围产结局,且早发型重度子痫前期孕妇早产儿、低体重儿的发生率明显增加,相关新生儿疾病(如RDS、新生儿窒息等)的发病率也明显增加,但SGA及红细胞增多症等疾病的发生率与发病孕周无关。
Objective To investigate the relationship between gestational age and perinatal outcome in patients with severe preeclampsia. Methods 112 cases of severe preeclampsia in our hospital onset time of 34 weeks gestational age, divided into early-onset and late-onset groups, namely 55 pregnant women in group A, 59 newborns, 57 pregnant women in group B, newborns 62 cases, the two groups of pregnant women and childbirth newborns general clinical data, the incidence of neonatal disease and perinatal outcomes were analyzed and compared. Results (1) There was a significant difference in gestational weeks and preterm birth between two groups (P <0.01). (2) The average gestational age, average birth weight and average length at birth of the two groups were statistically There were significant differences (P <0.01) .A group of 41 newborns with low birth weight (incidence of 69.49%), B group of 17 cases (27.42% incidence), the two groups were statistically significant differences P (0.01) .In group A, 11 cases (18.64%) were smaller than gestational age (SGA), 46 cases (77.97%) were suitable for gestational age (AGA), 2 cases (3.39% (22.58%), AGA 40 (65.57%), and LGA 8 (12.90%) in group B. There was no significant difference between the two groups (P> 0.05). (3) The incidence of deformities, neonatal asphyxia, respiratory diseases, acidosis and glucose metabolism disorders were statistically different (P (0.05)) .Compared with other kinds of diseases, there was no statistical significance. (4) Comparison The incidence of adverse pregnancy outcomes in the two groups of pregnant women was 6 cases in early hair group and 0 in late hair group, with significant difference between the two groups (P = 0.012) .Conclusion The incidence of preeclampsia has a direct impact on gestational age Perinatal outcome, and early hair type weight Pre-eclampsia pregnant women premature children, low birth weight children significantly increased the incidence of related neonatal diseases (such as RDS, neonatal asphyxia, etc.) the incidence also increased significantly, but the incidence of SGA and polycythemia and other diseases and the incidence Pregnancy has nothing to do.