论文部分内容阅读
目的探讨新生儿缺氧缺血性脑病(HIE)与孕妇妊娠期高血压之间的关系。方法选择我院2006年1月至2009年1月收治的HIE患儿283例作为患儿组,同期选择产科足月适于胎龄儿108例作为对照组,对患儿组和对照组母亲的血压进行统计分析;进一步将HIE分为轻、中、重度3组,对3组患儿母亲血压值进行统计分析。结果对照组平均收缩压(SBP)为(116.71±12.56)mmHg,舒张压(DBP)为(87.23±5.11)mmHg;患儿组SBP为(144.28±16.49)mmHg,DBP为(89.45±9.38)mmHg,两组SBP差异有统计学意义(P<0.05);患儿组重度子痫前期和子痫发生率分别为34.6%和2.8%,对照组则无重度子痫前期和子痫发生。轻度HIE患儿母亲SBP为(139.75±13.31)mmHg,DBP为(86.48±9.41)mmHg;中度HIE患儿母亲SBP为(141.77±15.94)mmHg,DBP均值(88.87±7.49)mmHg;重度HIE患儿母亲SBP为(160.23±19.84)mmHg,DBP为(93.27±6.11)mmHg,无论是SBP还是DBP,重度HIE患儿母亲与轻度、中度HIE患儿母亲相比,差异均有统计学意义(P<0.05)。结论妊娠期女性SBP较DBP与HIE关系更为密切,重度HIE患儿母亲SBP和DBP升高尤为显著。
Objective To investigate the relationship between neonatal hypoxic-ischemic encephalopathy (HIE) and gestational hypertension in pregnant women. Methods A total of 283 HIE children admitted to our hospital from January 2006 to January 2009 were enrolled in this study. In the same period, 108 cases of full-term suitable gestational age were selected as the control group. The blood pressure was analyzed statistically. HIE was further divided into mild, moderate and severe groups, and the blood pressure of the three groups of children were statistically analyzed. Results SBP was (116.71 ± 12.56) mmHg and (DBP) was (87.23 ± 5.11) mmHg in control group, SBP was (144.28 ± 16.49) mmHg, and DBP was (89.45 ± 9.38) mmHg (P <0.05). The incidence of severe preeclampsia and eclampsia was 34.6% and 2.8% respectively in the two groups, but no severe preeclampsia and eclampsia in the control group. The SBP was (141.97 ± 15.94) mmHg and the mean DBP was (88.87 ± 7.49) mmHg) in mild HIE infants with mild HIE. The mean SBP was (139.75 ± 13.31) mmHg and the DBP was (86.48 ± 9.41) The SBP was (160.23 ± 19.84) mmHg and the DBP was (93.27 ± 6.11) mmHg in both mothers and infants with severe HIE compared with that of mothers with mild and moderate HIE, both SBP and DBP Significance (P <0.05). Conclusion The SBP in gestation women is more closely related to DBP and HIE, especially in mothers with severe HIE.