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重症肝炎30例随机分为两组,采用综合疗法治疗15例;另15例在综合疗法基础上加用人胎肝细胞悬液。综合治疗组病死比例为9/15例;胎肝组病死比例为4/15例,较综合疗法组明显为低。胎肝组存活11例平均退黄时间为55.4±25.4天;综合疗法组存活6例,平均退黄时间为119.7±54.9天,前者明显短于后者(P<0.01)。对胎肝组12例患者作输注前后凝血酶元时间活动度对比观察,输注后48h凝血酶元时间活动度可提高18.9％。
Severe hepatitis 30 patients were randomly divided into two groups, the use of comprehensive treatment of 15 cases; the other 15 cases based on the combined treatment of fetal liver cell suspension. In the comprehensive treatment group, the rate of death was 9/15; in the fetal liver group, the rate of death was 4/15, which was significantly lower than that in the combination therapy group. In the fetal liver group, the average age of rehmannia in 11 cases was 55.4 ± 25.4 days. In the combination therapy group, 6 cases survived. The mean time to rehmannia was 119.7 ± 54.9 days, the former was significantly shorter than the latter (P <0.01). Twelve patients in fetal liver group were compared before and after the infusion of thrombin time activities, and the activity of thrombin in time after 48 hours infusion increased by 18.9%.