Synthesis of N1-Substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyra- zolethiocarboxamide as Novel Smal

来源 :中国化学快报 | 被引量 : 0次 | 上传用户：gengyunshe

【摘要】

：

A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some de

【作者】

：

Chun GUO Xiao Hui DU James H.M

【机构】

：

School of Pharmaceutical Engineering,School of Pharmacy

【出处】

：

中国化学快报

【发表日期】

：

2004年期

【关键词】

：

N1-substituted-3-aryl-4-alkyl-4 5-dihydro-1H-1-pyrazolethiocarboxamide synthesis

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A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some derivatives were found to be active against the cysteine protease of T.cruzi..

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Synthesis of N1-Substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyra- zolethiocarboxamide as Novel Smal

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