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对糖尿病胃肠道并发症的发病机理目前了解较少。Goyal和Spiro提出以下5点:1.内脏神经病变;2.微血管病变;3.血糖和电介质水平异常;4.继发感染的可能性增大;5.激素(如胰岛素和胰高血糖素)量的改变。最重要的基本病变看来发生在内脏自主神经,据认为是胃肠道运动功能和肌张力减低的原因,也能造成消化液分泌如胰液的分泌减少。但尚无确证说明这些机能紊乱与特异的解剖改变有关。
The pathogenesis of gastrointestinal complications of diabetes is currently less understood. Goyal and Spiro make the following five points: 1. Visceral neuropathy; 2. Microangiopathy; 3. Abnormal glucose and dielectric levels; 4. Increased likelihood of secondary infection; 5. Hormones, such as insulin and glucagon The amount of change. The most important basic lesion appears to occur in the visceral autonomic nerve, which is believed to be the cause of decreased gastrointestinal motility and hypotonia, as well as reduced secretion of digestive juice such as reduced secretion of pancreatic juice. However, there is no conclusive evidence that these disorders are associated with specific anatomic changes.