帕金森病是一种慢性致残性疾病，系黑质纹状体多巴胺能神经元变性，引起多巴胺减少所致。其主要临床症状为静止性震颤、强直和运动减少。迄今基本的治疗药物仍为左旋多巴。尽管合并应用多巴脱羧酶（ＤＤＣ）抑制剂可通过促进左旋多巴吸收进而增强其生物利用度，但大量的左旋多 Parkinson’s disease is a chronic disabling disease that degeneration of the nigrostriatal dopaminergic neurons, resulting in a decrease in dopamine. The main clinical symptoms of resting tremor, decreased rigidity and exercise. So far the basic treatment of drugs is still levodopa. Although the combined use of dopamine decarboxylase (DDC) inhibitors can enhance their bioavailability through the promotion of levodopa absorption, a large amount of levo-D