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原发性肝癌是我国常见恶性肿瘤之一[1],居我国癌症发病率的第二位,每年约有13万人死于肝癌,以东南沿海地区高发。近些年来其发病率和死亡率有逐年升高的趋势。由于其具有侵袭性强,易复发、转移等生物学特性,目前包括手术、放疗、化疗等各种治疗方法的效果均不佳。本文就原发性肝癌的生物治疗的研究进展作一综述。
Primary liver cancer is one of the common malignant tumors in China [1], ranking the second place in the incidence of cancer in our country. About 130,000 people die of liver cancer each year, and are endemic to the southeast coastal areas. In recent years, its morbidity and mortality have been increasing year by year. Because of its invasive, easy to recurrence, metastasis and other biological characteristics, including surgery, radiotherapy, chemotherapy and other treatments are not effective. This article reviews the research progress of biotherapy for primary liver cancer.