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为探讨胃炎丸治疗慢性胃炎在改善胃肠动力方面的作用,对33例慢性胃炎患者进行临床观察,并选择胃肠墨汁推进试验及胃酚红排空试验进行了动物实验。研究结果胃炎丸能明显改善症状,提高血清胃动素水平(P<0.05).促进胃排空,治疗前、后胃排空率分别为(20.1±6.1)%、(30.3±7.6)%(P<0.05),从而有利于胃粘膜的修复。动物实验也证实胃炎丸具有提高小鼠胃肠墨汁推进运动及加快大鼠酚红的排空作用。提示胃炎丸能调整胃肠动力,改善胃的内环境,从而对慢性胃炎具有较好的治疗效果。
To investigate the effect of Weiyan Pill in the treatment of chronic gastritis on improving gastrointestinal motility, 33 patients with chronic gastritis were observed clinically, and gastrointestinal ink advancing test and gastric phenol red emptying test were selected for animal experiments. The results of Weiyan Pill can obviously improve the symptoms and increase the level of serum motilin (P<0.05). Promoting gastric emptying, the gastric emptying rate before and after treatment was (20.1±6.1)% and (30.3±7.6)% (P<0.05), which was beneficial to the repair of gastric mucosa. Animal experiments also confirmed that Weiyan Pill has the effect of increasing the motility of mice’s gastrointestinal ink and accelerating the emptying of phenol red in rats. Tips Weiyan Pill can adjust gastrointestinal motility, improve the internal environment of the stomach, and thus have a better therapeutic effect on chronic gastritis.