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目的探讨氨溴特罗与复方异丙托溴铵在小儿毛细支气管炎中的疗效。方法选择我院2010年2月至2012年2月毛细支气管炎患儿共100例,均符合毛细支气管炎诊断标准,上述患儿随机分为观察组和对照组。对照组患儿常规给予吸氧、控制喘憋、给予抗生素抗感染、抗病毒、镇咳祛痰、退热等治疗。观察组患儿在上述治疗基础上给予氨溴特罗口服液,同时给予复方异丙托溴铵。治疗后评定两组治疗效果。结果观察组治疗后临床效果评定结果:显效36例、有效11例,无效3例;观察组总有效率为94.0%。对照组治疗后临床效果评定结果:显效27例、有效12例,无效11例;观察组总有效率为78.0%。观察组总有效率高于对照组(P<0.05)。结论氨溴特罗与复方异丙托溴铵在小儿毛细支气管炎中的疗效显著,改善患儿气促、喘憋等症状显著,值得借鉴。
Objective To investigate the efficacy of ambroxol and ipratropium bromide in children with bronchiolitis. Methods A total of 100 children with bronchiolitis were selected from February 2010 to February 2012 in our hospital. All of them met the diagnostic criteria of bronchiolitis. The children were randomly divided into observation group and control group. Children in the control group were routinely given oxygen, controlled wheezing, anti-infective antibiotics, anti-virus, antitussive expectorant, antipyretic treatment. Patients in the observation group were given the ambroxol oral solution on the basis of the above treatment, and the compound ipratropium bromide was given at the same time. After treatment, the two groups were evaluated. Results The results of the clinical evaluation of the observation group after treatment: 36 cases markedly effective in 11 cases, 3 cases ineffective; observation group, the total effective rate was 94.0%. The results of the clinical evaluation of the control group after treatment: 27 cases markedly effective in 12 cases, 11 cases ineffective; observation group, the total effective rate was 78.0%. The total effective rate in observation group was higher than that in control group (P <0.05). Conclusion The efficacy of ambroxol and ipratropium bromide in children with bronchiolitis is significant. It is worth learning from the improvement of the symptoms such as shortness of breath and wheezing in children.