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目的探讨抗HPV生物蛋白隐形膜在宫颈感染高危型人乳头瘤病毒(HR-HPV)的治疗效果。方法选择在门诊做宫颈癌筛查,宫颈液基细胞学检测(TCT)报告正常,HR-HPV(+)的女性共68例,随机分为二组,治疗组38例,使用抗HPV生物蛋白隐形膜治疗3个疗程;对照组30例,使用重组人干扰素α2a栓,治疗3个疗程,治疗结束3~4周复查两组女性的HR-HPV的情况,分析临床疗效。结果治疗组38例HR-HPV(+)转阴性率52.6%,对照组30例HR-HPV(+)转阴性率26.7%。治疗组转阴率明显高于对照组,两组对比P<0.05,具有统计学意义。结论抗HPV生物蛋白隐形膜在治疗宫颈感染HR-HPV有明显效果。
Objective To investigate the therapeutic effect of anti-HPV bioprotein invisible film on high risk human papillomavirus (HR-HPV) in cervical infection. Methods A total of 68 women with normal HR-HPV (+) were enrolled in this study. They were randomly divided into two groups. The treatment group (38 cases) received anti-HPV bio-protein Invisible membrane treatment of three courses; control group of 30 cases, the use of recombinant interferon α2a suppository, the treatment of three courses of treatment of 3 to 4 weeks after the review of the two groups of women’s HR-HPV situation, analysis of clinical efficacy. Results The negative rate of HR-HPV (+) in the treatment group was 52.6%, while the negative rate of HR-HPV (+) in the control group was 26.7%. The negative conversion rate of the treatment group was significantly higher than that of the control group, P <0.05 compared with the two groups, with statistical significance. Conclusion The anti-HPV bio-protein stealth membrane is effective in treating cervical infection of HR-HPV.