2,5-二氯硝基苯为一种氮肥增效剂,对提高农作物的产量有一定的作用。我们于1978～1980年对其纯品进行了急性毒性和亚急性毒性试验,并进行了致畸和骨髓细胞微核试验。浙江医科大学进行了 Ames 法致突变试验,证明该化学物质系碱基置换型终末诱变物,能引起鼠伤寒沙门氏菌突变种 TA_(100)的回变。为了进一步探讨其致突变作用, 2,5-Dichloronitrobenzene is a nitrogen fertilizer synergist, to improve the yield of crops to a certain extent. We conducted acute toxicity and subacute toxicity tests on their pure products from 1978 to 1980, and conducted teratogenic and myeloid micronucleus tests. Ames mutagenesis test was carried out in Zhejiang Medical University, which proved that the chemical was a base-substitution terminal mutagen, which caused the TA_ (100) mutation of the Salmonella typhimurium mutant TA_ (100). In order to further explore its mutagenic effect,