艮他霉素与托普霉素的抗菌作用相似,体外试验中以艮他霉素对沙雷氏菌族的作用较好,而后者则对绿脓杆菌的作用较好,两者的药物动力学性质亦完全一致;初步动物实验结果显示托普霉素的急性毒性、耳毒性及肾毒性较艮他霉素为 Gentamicin and tobramycin antibacterial effect similar to in vitro experiments with gentamicin on Serratia bacteria better role, while the latter is better on Pseudomonas aeruginosa, both the pharmacokinetic The nature of the study is also completely consistent; preliminary animal experiments showed that the acute toxicity, ototoxicity and nephrotoxicity of tobramycin compared with gentamicin