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目的观察短期模拟失重对立位心肺循环功能的影响,为进一步研究失重时心血管功能下降机理积累资料。方法6名健康男性被试者,头低位6°卧床7d。分别观察卧床前、后立位心肺循环功能的变化。心肺循环功能检测选用XXH-2000型小循环心功能检测仪。结果头低位卧床7d致被试者立位耐力降低,卧床后右心室射血期(j-z)缩短,右心室排血效率降低(Q-j/j-z升高),提示右心功能减退。心血管调节适应性反应减弱,右心功能储备降低。结论c波高度(hc)、c波高度与Z波高度的比值(hc/hz)可作为评价立位耐力或预测立位晕厥的指标;小循环心功能检测法评价立位心肺循环功能的变化有一定的前景。
Objective To observe the effects of short-term simulated weightlessness on cardiopulmonary bypass and to accumulate data for further study on the mechanism of cardiovascular function decline during weightlessness. Methods Six healthy male subjects, head low 6 ° bedridden 7d. Respectively observe the changes of cardiopulmonary circulatory function before and after bed rest. Cardiopulmonary bypass function test selection XXH-2000-based small heart function detector. Results In the first 7 days of bed rest, the subjects’ standing endurance decreased, the right ventricular ejection period (j-z) shortened and the right ventricular ejection efficiency decreased (Q-j / j-z increased) Decreased. Adaptive response to cardiovascular regulation weakened, lower right ventricular reserve. Conclusions The ratio of c-wave height (hc), c-wave height to Z-wave height (hc / hz) can be used as an index to evaluate standing standstill or predict standstill syncope; the microcirculation cardiometry test evaluates the change of standing cardiopulmonary bypass Have a certain future