风湿性心脏病NK细胞活性的变化及其临床意义

来源 :综合临床医学 | 被引量 : 0次 | 上传用户:xiuxiumumu
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本文对50例风湿性心脏病患者外周血NK细胞活性的变化进行了研究,结果:风湿活动组NK细胞活性明显降低,而非风湿活动组NK活性与对照组相比无显著差异.认为NK细胞活性降低与免疫反应调节失控有关,同时NK细胞功能缺陷本身,又进一步加剧了免疫调节功能紊乱,加重了心肌及心瓣膜的免疫损害. In this paper, 50 patients with rheumatic heart disease in patients with NK cell activity changes were studied, the results: rheumatoid activity group NK cell activity was significantly reduced, while non-rheumatoid activity group NK activity was no significant difference compared with the control group that NK cells Decreased activity and regulation of immune response out of control related to the same time, NK cell function itself, but also further exacerbated the immune dysfunction, increased cardiac and cardiac valve immune damage.
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