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磷脂酶A2(PhospholipaseA2,PLA2)是磷脂C-2位酰基水解酶的简称,它以生物膜磷脂为天然底物,催化多种磷脂C-2位脂酰键水解产生游离脂肪酸和溶血磷脂,其产物可成为细胞内的第二信使分子或进一步代谢为脂类炎症介质的前体,参与炎症反应、细胞增
Phospholipase A2 (PLA2) is short for phospholipid C-2 acyl hydrolase. It uses biofilm phospholipid as a natural substrate to catalyze the hydrolysis of various fatty acyl bonds at the C-2 position of phospholipids to produce free fatty acids and lysophospholipids. The product may become a second messenger molecule within the cell or be further metabolized into a precursor of a lipid inflammatory mediator, involved in the inflammatory response,