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目的建立本实验室IgE健康成人参考值,探讨IgE的水平是否存在性别、年龄、季节的差异。方法将345例健康体检者按性别、年龄和季节分组,空腹采血,采用电化学发光法测定其IgE的水平,将结果进行统计分析,IgE参考值取97.5%可信度上限。结果男女IgE的参考值分别为≤706.2ng/ml和≤769.56ng/ml,除性别差异有统计学意义(P<0.001)外,在不同年龄组、季节组间,IgE水平差异均无统计学意义(P>0.05)。结论 IgE水平与受试者性别密切相关,各临床实验室应根据受试者不同性别建立实验室内IgE的参考值范围。
Objective To establish a reference value of IgE healthy adults in our laboratory and discuss whether IgE level has gender, age or season difference. Methods 345 healthy subjects were divided into groups according to sex, age and season, fasting blood was collected. The level of IgE was determined by electrochemiluminescence. The results were statistically analyzed. The upper limit of IgE reference was 97.5%. Results The IgE values of both men and women were ≤706.2ng / ml and ≤769.56ng / ml, respectively. There were no significant differences in IgE levels between different age groups and seasonal groups except sex difference (P <0.001) Significance (P> 0.05). Conclusion The level of IgE is closely related to the gender of the subjects. Each clinical laboratory should establish a reference range of laboratory IgE according to the sex of the subjects.