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目的 探讨超声在早期卵巢癌诊断中的价值。方法 分析经超声、肿瘤标记物CA12 5检查 ,并经手术及病理证实的早期卵巢癌患者 47例。结果 肿瘤呈囊性 2 9例 ,内有乳头或实性成分 ,单房 5例 ,多房 2 4例 ;囊实性 13例 ;实性 5例。超声发现卵巢病变 46例 ,诊断卵巢恶性病变 42例。术前超声诊断的敏感性、特异性、阳性预测值和阴性预测值分别为 89.4%、92 .7%、43 .8%和 99.3 %。 47例早期卵巢癌患者中 ,CA12 5 >3 5U /ml者 2 4例 ,敏感性、特异性、阳性预测值和阴性预测值分别为 5 1.1%、90 .2 %、2 5 .0 %和 96.7%。超声对早期卵巢癌的敏感性较血清CA12 5高 (P <0 .0 1)。结论 超声在早期卵巢癌诊断中起着重要的作用 ,为早期卵巢癌的首选检查方法。
Objective To investigate the value of ultrasound in the diagnosis of early ovarian cancer. Methods Forty-seven patients with early ovarian cancer confirmed by ultrasonography, tumor marker CA12 5 and confirmed by surgery and pathology were analyzed. Results The tumor was cystic 29 cases, there are nipples or solid components, single room in 5 cases, multiple rooms in 24 cases; cystic solid in 13 cases; solid in 5 cases. Ovarian lesions were found in 46 cases by ultrasound, and 42 cases were diagnosed as ovarian malignant lesions. The sensitivity, specificity, positive predictive value and negative predictive value of preoperative ultrasonography were 89.4%, 92.7%, 43.8% and 99.3%, respectively. 47 cases of early ovarian cancer patients, CA12 5> 35U / ml were 24 cases, the sensitivity, specificity, positive predictive value and negative predictive value were 51.1%, 90.2%, 25.5% and 96.7%. The sensitivity of ultrasound to early ovarian cancer was higher than that of serum CA12 5 (P <0.01). Conclusion Ultrasound plays an important role in the diagnosis of early ovarian cancer and is the first choice of early ovarian cancer.