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目的：探讨克林霉素联合庆大霉素治疗慢性盆腔炎的临床疗效和安全性。方法：将86例慢性盆腔炎患者分为两组，对照组采用庆大霉素联合甲硝唑治疗，观察组采用克林霉素联合庆大霉素治疗，均连续治疗2周观察两组临床疗效和不良反应，并观察两组治疗前后临床症状积分变化。结果：观察组总有效率93.02%显著高于对照组的79.07%，不良反应发生率11.63%显著低于对照组，差异有统计学意义（P＜0.05）；两组治疗后临床症状积分均较治疗前显著降低，且观察组治疗后低于对照组治疗后，差异有统计学意义（P＜0.05）。结论：克林霉素联合庆大霉素治疗慢性盆腔炎临床疗效显著，可以有效改善患者的临床症状，且不良反应少，值得临床积极推广。“,”Objective To explore the efficacy and safety of clindamycin and gentamicin in the treatment of chronic pelvic inflammatory disease.Methods 86 cases of chronic pelvic inflammation patients were divided into two groups, the control group using gentamicin and metronidazole for treatment, the observation group were combined with clindamycin and gentamicin treatment, continuous treatment for 2 weeks to observe the clinical efficacy and adverse reactions of two groups, and observe the changes of integral the clinical symptoms of the two groups before and after treatment.Results The total effective rate of observation group (93.02%) was significantly higher than the control group 79.07%, the incidence of adverse reactions (11.63%) was significantly lower than the control group, the difference was statistically significant (P < 0.05); the two groups clinical symptom scores after treatment were significantly lower than those before treatment, and the patients in the observation group than in the control group after treatment. The difference was statistically significant (P< 0.05).Conclusion Clindamycin and gentamicin have significant therapeutic effect in the treatment of chronic pelvic inflammatory disease, can effectively improve the clinical symptoms of patients Shape, and less adverse reactions, it is worth clinical promotion positively.