在肿瘤组织中只有少部份细胞不断地增殖,而大部份肿瘤细胞处于不增殖或很有限增殖的状态。这种具有不断增殖能力的细胞群体是肿瘤干细胞,肿瘤干细胞一方面通过增殖进行自我更新(self renewal),另一方面可通过分化逐步变成失去增殖能力的分化细胞,两种细胞通常保持着一种动态平衡。还有一部份 Only a small number of cells in the tumor tissue continuously proliferate, and most tumor cells are in a state of non-proliferation or very limited proliferation. The cell population that has continuously proliferating ability is cancer stem cells. On the one hand, cancer stem cells self-renewal through proliferation, and on the other hand, they can gradually become differentiated cells that lose their proliferative capacity through differentiation. The two types of cells usually maintain one. Dynamic balance. There is also a part