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结肠黑变病国外文献报道较多，国内文献很少。我们收集解放军总医院１９８５～１９９０年２２８３例纤维结肠镜检查中发现的黑色病变并取活检经病理证实的１３４例进行临床病理分析，主要对其中２２例进行超微结构观察。结果发现结肠黑变病是一种较常见的大肠病变，与便秘和服用泻药关系不密切。电镜观察见纤维母细胞亦有吞噬色素的现象等。说明对中国人的大肠黑变病有必要进行深入的研究。
Colitis melanosis more foreign literature reports, domestic literature rarely. We collected 2283 cases of colon disease found in PLA General Hospital from 1985 to 1990 and performed biopsy of 134 cases confirmed by pathology for clinicopathological analysis. The ultrastructure of 22 cases were observed. The results found that colorectal disease is a more common colorectal lesions, and constipation and taking laxatives are not closely related. Electron microscopy see also fibroblast phagocytosis phenomenon. Description of Chinese people’s colorectal disease is necessary for in-depth study.