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胚胎干细胞(ESC)是一种多潜能细胞,可在体外培养时保持未分化状态,并具有分化为特定体细胞的潜能,包括心肌细胞。ESC可提供大量分化的心肌细胞用于使受损的心肌层再生的治疗。目前ESC在心血管疾病治疗方面的研究仍处于基础环节,现将相关问题作一综述。
Embryonic stem cells (ESCs) are pluripotent cells that remain undifferentiated during in vitro culture and have the potential to differentiate into specialized somatic cells, including cardiomyocytes. ESC can provide a large number of differentiated cardiomyocytes for the treatment of damaged myocardium. At present, the research of ESC in the treatment of cardiovascular diseases is still at the basic stage, and the related problems are summarized.