原发性肝癌简称肝癌,是指由肝细胞或者肝内胆管上皮细胞发生的恶性肿瘤,是我国常见的恶性肿瘤之一,其病死率在恶性肿瘤中居第2位。全世界每年约有25万人死于肝癌,而我国约占其中的45%。细胞凋亡的概念在1972年由Kerr等提出,细胞凋亡是指细胞在一定的生理、病理条件下,遵循一定的程序,通过细胞内基因及其产物的调控而发生的一种程序性细胞死亡。近年来众多研究证实,细胞凋亡的调控与肿瘤的发生、发展、消退等存在着紧密 Primary liver cancer referred to as liver cancer, refers to the liver cells or intrahepatic bile duct epithelial cells of malignant tumors, is one of the common malignant tumors in our country, the case fatality rate ranks second in malignant tumors. About 250,000 people die of liver cancer each year in the world, and our country accounts for about 45% of them. The concept of apoptosis was proposed by Kerr et al. In 1972. Apoptosis is a kind of programmed cell that takes place under certain physiological and pathological conditions and under the control of a certain gene and its product. death. In recent years, many studies have confirmed that the regulation of apoptosis and tumor occurrence, development, regression and so there is close