免疫性血小板减少症(immune thrombocytopenia,ITP)是因体液和细胞免疫介导的血小板过度破坏以及血小板生成不足,导致血小板减少的获得性自身免疫性疾病,目前对ITP的发病原因尚未明了。人体免疫功能的正常运行,需要依靠凋亡和增殖两个途径调节相关细胞及细胞因子分泌水平的平衡来实现。研究认为,ITP患者存在多种免疫细胞及细胞因子的异常分泌,导致血小板生成不足和破坏过多的根源可能是细胞凋亡途径和增殖途 Immune thrombocytopenia (ITP) is an acquired autoimmune disease that results in thrombocytopenia due to excessive platelet destruction mediated by humoral and cellular immunity and insufficient platelet production. The pathogenesis of ITP is unknown at present. The normal operation of human immune function, need to rely on apoptosis and proliferation of two ways to regulate the balance of relevant cells and cytokine secretion to achieve. Studies suggest that there is a variety of ITP patients with abnormal secretion of immune cells and cytokines, leading to inadequate platelet destruction and destruction of the root cause may be apoptotic pathway and proliferation