IL 8是一种人单核细胞衍化的中性粒细胞趋化因子,并作为T 淋巴细胞的趋化因子。尽管有些实验表明IL-8对中性粒细胞有一些作用,但对IL-8的脱颗粒特性了解甚少。本文作者研究了纯化的天然IL-8对中性粒细胞脱颗粒作用,并与TNF-a、IL-1β和IL-6等单核因子作了比较。作者首先从正常静脉血里分离出人颗粒细胞,然后分别加相同体积的天然人IL-1β13(10~8U/mg),IL-6(10~9U/ IL 8 is a human monocyte-derived neutrophil chemokine and serves as a chemokine for T lymphocytes. Although some experiments have shown that IL-8 has some effects on neutrophils, little is known about the degranulation properties of IL-8. The authors studied the effect of purified native IL-8 on neutrophil degranulation and compared it with monokines such as TNF-α, IL-1β and IL-6. The authors first isolated human granulosa cells from normal venous blood, then added the same volume of native human IL-1β13 (10-8 U / mg), IL-6 (10-9 U /