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目的:观察化浊解毒方联合三联疗法治疗胃溃疡的临床效果。方法:将我院2013年1月~2014年1月收治的120例胃溃疡患者作为研究对象,按随机数字表法将其分为观察组与对照组2组,各60例。对照组给予常规三联疗法处理,观察组在此基础上加用中药化浊解毒方治疗,比较2组患者的临床疗效,记录治疗前后2组患者中医症候积分的改善情况,统计不良反应发生率。结果:观察组临床治疗有效率为98.33%,对照组临床有效率为78.33%,2组治疗有效率对比差异有统计学意义(P<0.05);治疗前,2组患者腹痛、烧心、反酸及嗳气症状积分对比差异无统计学意义(P>0.05);治疗后,观察组腹痛、烧心、反酸及嗳气症状积分与对照组相比差异有显著统计学意义(P<0.05);观察组不良反应发生率为10.00%,明显低于对照组的38.33%,组间对比差异有统计学意义(P<0.05)。结论:在胃溃疡患者的临床治疗中,为优化临床疗效,降低治疗不良反应发生率,缩短患者的症状改善时间,提倡在常规三联方案的基础上加用中药化浊解毒方。
Objective: To observe the clinical effect of Huazhuo Jiedu Decoction combined with triple therapy in the treatment of gastric ulcer. Methods: One hundred and twenty patients with gastric ulcer admitted from January 2013 to January 2014 in our hospital were divided into observation group and control group according to the random number table method, with 60 cases in each group. The control group was treated with conventional triple therapy. The observation group was treated with Huazhuo Jiedu Decoction on this basis. The clinical curative effect was compared between the two groups. The improvement of TCM symptom score before and after treatment was recorded and the incidence of adverse reactions was recorded. Results: The effective rate of clinical treatment in observation group was 98.33%, and the clinical effective rate in control group was 78.33%. There was significant difference between the two groups (P <0.05); before treatment, abdominal pain, heartburn, acid reflux (P> 0.05). After treatment, the scores of abdominal pain, heartburn, acid reflux and asthma symptom in the observation group were significantly different from those in the control group (P <0.05); the observation group The incidence of adverse reactions was 10.00%, which was significantly lower than that of the control group (38.33%). The difference between the two groups was statistically significant (P <0.05). Conclusion: In the clinical treatment of patients with gastric ulcer, in order to optimize the clinical efficacy, reduce the incidence of adverse reactions, shorten the time to improve the symptoms of patients, to promote the conventional triple program based on the use of traditional Chinese medicine Huazhuo detoxification side.