以紫外线（λ＝２３０～２６５ｎｍ）照射非致病尖孢镰刀菌３１６菌系，随着照射时间的增加，分生孢子的存活数逐渐减少，照射时间与存活菌株对农抗１２０和速克灵的变异频率间没有一定的相关性。对农抗１２０抗性增加的菌株仍保持３１６定殖西瓜幼苗导管的能力，对瓜苗的促生作用以及非致病性。在药板上用紫外线重复照射存活菌株后，获得的菌株对两种农药的变异频率均有提高，对农抗１２０的抗性有所下降，对速克灵的抗性显著提高。 The non-pathogenic strain Fusarium oxysporum 316 was irradiated with UV light (λ = 230 ~ 265nm). With the increase of irradiation time, the viability of conidia decreased gradually. There is no certain correlation between mutation frequency. Strains resistant to agronomy 120 still retain the ability of 316 to colonize watermelon seedling ducts, their pro-proliferative effects on melon seedlings, and their non-pathogenicity. After repeated irradiation of surviving strains with UV light on the plate, the frequency of mutation of the two pesticides was increased, the resistance to Nongkang 120 decreased, and the resistance to Sinkink increased significantly.