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目的:评估对无排卵型月经不调患者施予不同剂量孕激素治疗的效果。方法:选择2015年3月至2016年3月进入广州市天河区冼村街社区卫生服务中心接受诊治的无排卵型月经不调患者90例为观察对象,所有患者都选用孕激素实施治疗,根据药物剂量的不同,将所选病例分成低剂量组、中剂量组、高剂量组,各30例,评估3组患者给药治疗后的疗效。结果:3组患者的总有效率、月经出血量、持续时间比较,差异均无统计学意义(P>0.05),但是低剂量组患者的不适反应率显著低于中剂量组与高剂量组,差异具有统计学意义(P<0.05)。。结论:对无排卵型月经不调患者予以低剂量(100 mg)、中剂量(200 mg)、高剂量(400 mg)孕激素,都能取得较显著的用药疗效,且用药安全性较高。
Objective: To evaluate the effect of different doses of progestin on patients with anovulatory irregular menstruation. Methods: From March 2015 to March 2016, 90 cases of anovulatory irregular menstruation admitted to Xiancun Street Community Health Service Center, Tianhe District, Guangzhou were enrolled in this study. All patients were treated with progestin, The different doses of drugs, the selected cases were divided into low dose group, medium dose group, high dose group, 30 cases each, evaluate the efficacy of three groups of patients after treatment. Results: There was no significant difference in total effective rate, menstrual bleeding and duration between the three groups (P> 0.05), but the rate of discomfort in the low-dose group was significantly lower than that in the middle-dose group and the high-dose group, The difference was statistically significant (P <0.05). . CONCLUSIONS: The patients with anovulatory irregular menstruation can be treated with low dose (100 mg), medium dose (200 mg) and high dose (400 mg) progesterone, which can achieve more significant therapeutic effect and have higher safety.