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抗癌新药半合成三尖杉酯碱科研成果鉴定会,于1980年12月9日至12日在海南岛海口市召开。参加会议的代表75人。会议由卫生部主持。天然三尖杉酯碱是从我国三尖杉属植物中分离出来的一种对多种动物移植性肿瘤有明显抑制作用的生物碱。由于三尖杉酯碱的来源受到植物资源的限制,中国医学科学院药物研究所于1973年开始利用在植物中含量较高但无抗癌活性的三尖杉碱(又称粗榧碱),进行三尖杉酯碱的半合成,于1975年6月获得成功。1978年春又与上
The semi-synthetic harringtonine research achievement appraisal meeting for new anticancer drugs was held on December 9-12, 1980 in Haikou City, Hainan Island. 75 delegates attended the meeting. The meeting was chaired by the Ministry of Health. Natural harringtonine is an alkaloid isolated from China’s harringtonia and has a significant inhibitory effect on a variety of animal transplanted tumors. Since the source of harringtonine was limited by plant resources, the Institute of Materia Medica, Chinese Academy of Medical Sciences, began using harringtonine (also known as scopolamine), which has a high content in plants but no anticancer activity, in 1973. Semisynthesis of harringtonine was successful in June 1975. In the spring of 1978 it was again