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目的探讨体外受精-胚胎移植(IVF-ET)胚胎冷冻保存时间对冻融胚胎移植临床妊娠率的影响。方法将361个冻融移植周期按胚胎冷冻保存时间分为三组:1组:冷冻保存时间≤90天;2组:91~360天;3组:≥361天,比较三组间临床妊娠率的差异。结果 2组与1组比较,临床妊娠率显著升高(P<0.05),2组与3组比较无显著性差异(P≥0.05)。结论在胚胎冷冻保存90天内行解冻胚胎移植临床妊娠率降低;胚胎冷冻保存时间≥361天不影响临床妊娠率。
Objective To investigate the effect of IVF-ET embryo cryopreservation on the clinical pregnancy rate of frozen-thawed embryo transfer. Methods 361 freeze-thaw cycles were divided into three groups according to the embryo cryopreservation time: group 1: cryopreservation time ≤90 days; group 2: 91- 360 days; group 3: ≥361 days. The clinical pregnancy rates The difference. Results Compared with group 1, the clinical pregnancy rate in group 2 was significantly increased (P <0.05). There was no significant difference between group 2 and group 3 (P> 0.05). Conclusion The pregnancy rate of embryo transfer in thawed embryos is reduced within 90 days after cryopreservation. The embryo cryopreservation time of 361 days does not affect the clinical pregnancy rate.