Coffman曾用组合法计算了乙炔同系物的手性构型和非手性构型数,文的结果除原子数3—9是对的外,其余部是错误的。本文采用Pólya计数定理计算了乙炔同系物的手性和非手性构型数,并指出文献[1]产生错误的原因,同时给出了具有类似结构关系的二茂铁的烷基衍生物的手性和非手性构型数。 Coffman used the combination method to calculate the chiral configuration and the achiral configuration number of acetylene homologues. The result of the paper is wrong except that the number of atoms is 3-9. In this paper, we calculated the chiral and achiral configuration numbers of acetylene homologues by using the Pólya counting theorem. We also point out the reasons for the errors in [1] and give the alkyl derivatives of ferrocene with similar structural relationships Chiral and achiral configuration number.