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内皮细胞(EC)粘附分子包括血管细胞粘附分子-1(VCAM-1)、E-选择素(E-selectin)和细胞间粘附分子-1(ICAM-1),这些分子对于炎性细胞的吸附非常必要,最近,在许多血管炎性疾病损害中已检出循环形式的粘附分子。复发性口腔溃疡(ROU)具有一些血管炎疾病的特点。本研究的目的是将ROU患者和对照组中的cVCAM-1、cE-selectin、cICAM-1的水平进行比较。 研究对象为ROU患者和健康对照者各50例,其中7例ROU患者分别在溃疡发作期和间歇期采取血液标本,观察在ROU不同时期,cICAM-1、cVCAM-1和E-selectin的变化。将5%EDTA抗凝血的血浆分离
Endothelial cell (EC) adhesion molecules include vascular cell adhesion molecule-1 (VCAM-1), E-selectin and intercellular adhesion molecule-1 (ICAM- 1) Adsorption of cells is imperative, and recently, circulating forms of adhesion molecules have been detected in many lesions of vascular vasculitis. Recurrent oral ulcers (ROU) have some of the characteristics of vasculitic diseases. The aim of this study was to compare the levels of cVCAM-1, cE-selectin and cICAM-1 in ROU patients and controls. The subjects were ROU patients and healthy controls in 50 cases, of which 7 cases of ROU patients were taken during the attack and intermittent ulcer blood samples were observed at different periods of ROU, cICAM-1, cVCAM-1 and E-selectin changes. 5% EDTA anticoagulated plasma was separated