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天然免疫系统通过高度保守的模式识别受体(PRR)成为机体防御系统的第一道屏障,活化天然免疫系统进一步诱导获得性免疫;最具特征的PRR为Toll样受体(TLR),能够识别病原微生物及其产物[微生物病原相关分子模式(PAMP)]以及自身细胞降解产物[内源性死细胞损伤相关分子模式(DAMP)],活
The innate immune system, through its highly conserved pattern recognition receptors (PRRs), becomes the first barrier to the body’s defense system and activates the natural immune system to further induce adaptive immunity; the most characteristic PRRs are Toll-like receptors (TLRs) that recognize Pathogenic microorganisms and their products [microbial pathogen-associated molecular pattern (PAMP)] and autologous cellular degradation products [endogenous dead cell damage related molecular patterns (DAMP)], live