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目的 :观察国产盐酸去甲万古霉素眼内注射治疗细菌性眼内炎的效果。方法 :对临床诊断为细菌性眼内炎的 32例病人在局麻或全麻下行前房和 /或玻璃体腔注射盐酸去甲万古霉素 0 8～ 1mg ,每日观察病情变化 ,炎症 48小时无明显控制者 ,再注射丁胺卡那霉素 2 0 0～ 40 0 μg。结果 :32例病人中 31例有效 ,有效率 96 9%。炎症控制后 ,8例行晶状体及玻璃状体切除术 ,6例行晶状体针吸术 ,1例行晶状体囊外摘除联合人工晶状体植入术 ,1例行抗青光眼手术。视力提高者 2 5例 ,不变者 7例。不同程度眼球萎缩 5例。结论 :眼内注射国产盐酸去甲万古霉素 0 8～ 1mg是治疗细菌性眼内炎有效而安全可靠的方法。
Objective: To observe the effect of domestic norvancomycin hydrochloride intraocular injection in the treatment of bacterial endophthalmitis. Methods: Thirty-two patients with bacterial endophthalmitis clinically diagnosed as bacterial endophthalmitis were anesthetized under general anesthesia with anterior chamber and / or intravitreal injection of norvancomycin 0.08-1 mg daily for 48 hours No obvious controller, and then injected amikacin 200 ~ 40 0 μg. Results: Of the 32 patients, 31 cases were effective and the effective rate was 96.9%. After the inflammation was controlled, eight patients underwent vitrectomy and hysterectomy, six underwent needle aspiration, and one underwent extracapsular lens extraction and intraocular lens implantation. One patient underwent glaucoma surgery. 25 cases of improved vision, unchanged in 7 cases. Different degrees of eye atrophy in 5 cases. Conclusion: Intraocular injection of norvancomycin hydrochloride 0 8 ~ 1mg is an effective and safe method for the treatment of bacterial endophthalmitis.