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目的探讨热毒宁与利巴韦林联合应用于小儿急性上呼吸道感染治疗中的效果。方法选取69例小儿急性上呼吸道感染患儿,男43例,女26例,年龄5个月~13岁。将其随机分为观察组和研究组,观察组34例患儿在常规治疗的基础上采用利巴韦林治疗,研究组35例患儿在常规治疗的基础上采用热毒宁联合利巴韦林治疗,两组患儿均于用药3 d后进行疗效比较。结果研究组患儿在咽部充血消失时间、咳嗽停止时间、鼻塞、流涕停止时间以及退热时间均短于观察组,差异有统计学意义(P<0.05)。观察组患儿有效率为82.35%,研究组患者有效率为97.14%,两组患者临床治疗效果比较,研究组优于观察组,差异有统计学意义(P<0.01)。结论在小儿急性上呼吸道感染中采用热毒宁与利巴韦林联合治疗的方法可有效改善患儿的临床症状,且安全有效,具有临床价值。
Objective To investigate the effect of combination of revitina and ribavirin in the treatment of children with acute upper respiratory tract infection. Methods 69 children with acute upper respiratory tract infection were selected, including 43 males and 26 females, aged from 5 months to 13 years old. They were randomly divided into observation group and study group. 34 cases in observation group were treated with ribavirin on the basis of conventional treatment. 35 children in study group were treated with combination of rebaudioside and ribavirin Lin treatment, two groups of children were treated 3 d after the treatment effect comparison. Results The study group was shorter than the observation group in the disappearance of pharyngeal congestion, the time of cough stop, the stuffy nose, the stop of runny nose and the time of fever relief. The difference was statistically significant (P <0.05). The effective rate of the observation group was 82.35%, the effective rate of the study group was 97.14%. The clinical efficacy of the two groups was better than that of the observation group (P <0.01). Conclusion The combined treatment of Radixin and Ribavirin in children with acute upper respiratory tract infection can effectively improve the clinical symptoms of children and is safe and effective.