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从胃肠外接受不同综合化疗方案的35例患者中建立了依托泪忒的药动学参数,并分析了有关24h代谢动力学的所有62组数据资料。从样本中取出并经高效波相色谱(HPLC)或薄层层析(TLC)分离后,利用[252Cf]血浆解吸附作用物质分光镜检术(PDMS)法测定依托泊惑的含量。该法作为非挥
Pharmacokinetic parameters were established in 35 patients receiving different combination regimens of parenteral nutrition and all 62 groups of data on 24-h metabolites were analyzed. After removal from the sample and separation by high performance liquid chromatography (HPLC) or thin layer chromatography (TLC), the retentate content was determined using [252Cf] plasma desorption spectroscopy (PDMS). The law as a non-volatile