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目的观察心脏骤停患者采用大剂量肾上腺素进行抢救的效果。方法将92例心脏骤停患者随机分为观察组和对照组各46例。在常规抢救的基础上,对照组采用常规剂量的肾上腺素治疗,观察组则采用大剂量肾上腺素治疗,对比2组患者的复苏成功率和自主循环、呼吸恢复情况。结果观察组复苏成功率为47.83%高于对照组的26.09%,差异有统计学意义(P<0.05)。观察组自主循环恢复率和自主呼吸恢复率均高于对照组,差异有统计学意义(P<0.05)。2组存活>1d率比较差异无统计学意义(P>0.05)。结论和常规剂量肾上腺素治疗比较,大剂量对于心脏骤停患者具有更显著的抢救效果,有助于促进患者自主循环和呼吸的迅速恢复,提高心肺复苏的成功率,挽救患者的生命,临床应用价值更显著。
Objective To observe the effect of high-dose epinephrine rescue in cardiac arrest patients. Methods 92 patients with cardiac arrest were randomly divided into observation group and control group, 46 cases each. On the basis of routine rescue, the control group was treated with regular dose of epinephrine, while the observation group was treated with high dose of epinephrine. The success rate of resuscitation, spontaneous circulation and respiratory recovery were compared between two groups. Results The success rate of recovery in observation group was 47.83%, which was higher than that in control group (26.09%), the difference was statistically significant (P <0.05). The recovery rate of spontaneous circulation and spontaneous respiration in observation group were higher than those in control group, with statistical significance (P <0.05). There was no significant difference in the survival rate of> 1d between the two groups (P> 0.05). Conclusion Compared with conventional dose epinephrine treatment, high dose has more significant salvage effect for patients with cardiac arrest, which can help to promote spontaneous circulation and rapid recovery of respiratory, improve the success rate of cardiopulmonary resuscitation and save patients’ life. Clinical application More significant value.