论文部分内容阅读
在癫痫自发性大发作之后血浆催乳激素和皮质醇浓度增加。这些激素的分泌是山复杂的神经调节机制所控制。为此作者测定了19例癫痫患者夜间的血浆催乳激素和皮质激素浓度并以12名正常志愿者为对照。结果发现10名志愿者血浆皮质激素在午夜最低,2名在8Pm最低;10名在8Am,2名在4Am最高。癫痫的血浆皮质激素节律相似,即17例在午夜最低,2例在8pm和4Am最低,13例在8Am,5例在4Am最高。2组间在上述时间内血浆皮质激素平均浓度无显著差别。复习正常人的催乳素曲线,并结合夜间每30分钟采取的标本,得出以下结论:1.血浆催乳素的波动幅度与4小时一次的标本分析结果相同,即在5～28ng/ml范围。2.在8pm时具有高催乳素浓度的人,在10pm时浓度较低,其平均浓度为7.6ng/ml,与8pm时平均浓度(13ng/ml)比较,有显著差别(p<0.01)。3.不论是从全部标本来考虑(20.8±1.2ng/ml)还是从每4小时一次的标本来
Plasma prolactin and cortisol concentrations increase after spontaneous epileptic episodes. The secretion of these hormones is controlled by the complex neuronal regulatory machinery. For this reason, the authors measured plasma prolactin and corticosteroid concentrations in 19 patients with epilepsy at night and compared them to 12 normal volunteers. The results showed that the 10 volunteers had the lowest plasma corticosteroids at midnight, the lowest at 8Pm, the lowest at 8m, the second at 8Am and the second at 4Am. Seizures had similar plasma corticosteroid rhythms, the lowest in 17 at midnight, the lowest at 8pm and 4Am in 2 patients, the lowest at 8m in 13 patients and the highest in 4Am in 5 patients. There was no significant difference in the average plasma concentrations of corticosteroids between the two groups during the above period. Review the normal human prolactin curve, combined with specimens taken every 30 minutes at night, the following conclusions: 1. Plasma prolactin fluctuations and 4 hours once the same specimen analysis, that is in the range of 5 ~ 28ng / ml. 2. Persons with a high prolactin concentration at 8 pm had a lower concentration at 10 pm with a mean concentration of 7.6 ng / ml, a significant difference (p <0.01) from the mean concentration at 8 pm (13 ng / ml). 3. Whether it was from all specimens (20.8 ± 1.2 ng / ml) or from specimens taken every 4 hours