目的:观察针刺结合当归补血祛风汤对特发性眼睑痉挛(BEB)的影响.方法:采用前瞻性、随机试验设计,将105例BEB受试者按1:1:1随机分为针刺组、中药组和针药结合组.针刺组采用单纯针刺治疗,2次/周.中药组采用当归补血祛风汤口服,每日1剂.针药结合组采用针刺联合中药治疗.三组均治疗4周后观察疗效.主要疗效指标为扬科维奇评分(JRS),次要疗效指标为眼睑痉挛残疾指数(BSDI).结果:治疗4周后,三组的JRS总分均较治疗前显著下降(P<0.05),针药结合组较针刺组和中药组下降幅度大(P0.05).在JRS严重程度评分的降低幅度上,针药结合组大于中药组(P0.05).治疗后,三组BSDI评分均较治疗前显著下降(P0.05).结论:针刺和当归补血祛风汤单独或联合使用治疗BEB均有一定临床疗效,联合使用的疗效优于单独使用.“,”Objective: To evaluate the therapeutic efficacy of acupuncture plus Dang Gui Bu Xue Qu Feng Tang for benign essential blepharospasm (BEB). Methods: A prospective randomized controlled trial was performed. A total of 105 participants were randomized 1:1:1 into an acupuncture group, a herbal medicine group and an acupuncture plus herbal medicine group. Participants in the acupuncture group received manual acupuncture treatment, twice a week. Participants in the herbal medicine group received Dang Gui Bu Xue Qu Feng Tang, oral administration, once a day. Participants in the acupuncture plus herbal medicine group received both treatments. The therapeutic effects of the three groups were evaluated after four weeks of treatment. The primary outcome was the Jankovic rating scale (JRS) score, and the secondary outcome was the blepharospasm disability index (BSDI) score. Results: After four weeks of treatment, the JRS total scores significantly decreased in all three groups versus baseline (P<0.05). A greater reduction in the JRS total score was reported in participants in the acupuncture plus herbal medicine group (P0.05). The acupuncture plus herbal medicine group had a greater decrease in the JRS severity score than the herbal medicine group (P0.05). The BSDI scores significantly decreased in all three groups versus baseline (P0.05). Conclusion: It is effective in the treatment of BEB either to use acupuncture and Dang Gui Bu Xue Qu Feng Tang alone or in combination. The combination therapy shows a more significant effect than either of the treatment alone.