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一、贲门癌的定义由于原发于食管下端、贲门及贲门下方胃近端的恶性肿瘤均可浸润至食管-胃交界部,所以临床上习惯性将食管胃交界部腺癌泛称为贲门癌。日本学者将食管下端及胃上端各2cm之内的范围定为贲门区;美国学者将病灶中心位于食管-胃黏膜交界线上1 cm、下2 cm区域内的癌称为贲门癌;我国则将原发于或主要占据食管胃黏膜交界线下2cm 范围内的癌定为贲门癌。1998年国际胃癌联合会和国际食管疾病学会协作会议将解剖学上贲门的上、下5cm范围内的食管和胃发生的癌定义为贲门区域癌,并将该区域的肿瘤分为3个类型:I型,发生于远端食管黏膜的腺癌,通常起源于食管的特异性肠上皮化生区(即Barrett’s食管),能够从上方浸润食管-胃交界部;Ⅱ型,真正意义的贲门癌,指发生于解剖学贲门或食管-胃交界部的肠上皮化生区,又称交界部癌;Ⅲ型,贲门下的胃癌,并从下方浸润食管-胃交界部及食管的下端。
First, the definition of cardia cancer Since the primary in the esophagus at the bottom of the cardia and gastric proximal gastric cancer can be infiltrated into the esophagus - stomach junction, so clinically customary esophageal junction of adenocarcinoma pan called cardia cancer. Japanese scholars will esophageal lower end of the stomach and the upper 2cm within the scope of the cardia area; the United States scholar will focus on the esophageal-gastric mucosa at the junction of the line 1 cm, 2 cm under the area of cancer called cardia cancer; China will be Primary or predominantly occupy esophageal mucosa at the junction of 2cm within the boundaries of cancer as cardia cancer. In 1998 the International Association of Gastric Cancer and the International Society of Esophageal Disease collaborative meeting will be anatomical cardia upper and lower 5cm range of esophageal and stomach cancer is defined as cardiac area of cancer and the area of the tumor is divided into three types: Type I, an adenocarcinoma of the distal esophageal mucosa, usually originates from esophageal specific intestinal metaplasia (ie, Barrett’s esophagus) that infiltrates the esophageal-gastric junction from above; type II, the true cardia, Refers to the occurrence of anatomical cardia or esophageal - gastrointestinal junction of the intestinal metaplasia, also known as the junction of cancer; type III, gastric cardia gastric cancer, and infiltration under the esophageal - gastric junction and the lower esophagus.