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目的研究申克孢子丝菌野生株的致病性。方法制备申克孢子丝菌野生株的细胞悬液,注入小鼠体内,于接种后第1周开始至第10周,视发病情况每周分批处死、剖检,观察发病情况。结果从自然环境中分离的申克孢子丝菌通过不同注射途径进入小鼠体内后均可导致小鼠致病;其产生色素的黑色菌株与不产生色素的白色菌株致病性无差异(P>0.05);腹腔组与尾静脉组比较致病性有差异(P<0.05)。结论申克孢子丝菌的野生株均具有致病性;黑白菌株致病性无显著差异;不同的致病途径致病性不同。
Objective To study the pathogenicity of wild strains of Spirulina. Methods The cell suspension of the wild strain of Spirulina schisandra was prepared and injected into the mice. The mice were sacrificed every week from week 1 to week 10 of the inoculation. The incidence of the disease was observed. Results Sporicons isolated from the natural environment through different routes of injection into mice can lead to pathogenicity in mice; the black pigment-producing strains and non-pigmented white strain pathogenicity was no difference (P> 0.05). There was significant difference in pathogenicity between abdominal cavity group and tail vein group (P <0.05). Conclusions The pathogenicity of wild strains of Spirorubricin was confirmed. There was no significant difference between the pathogenicity of black and white strains. The pathogenicity of different pathogenic agents was different.