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粘附分子与肿瘤转移密切相关已人所共知 ,但与化疗耐药的关系尚未引起普遍重视。本文就肿瘤细胞粘附分子CD44、整合素、ICAM 1和E 钙粘蛋白表达和化疗耐药的关系研究进展综述如下。
Adhesion molecules and tumor metastasis are closely related to the well-known, but the relationship with chemoresistance has not yet caused widespread attention. This review summarizes the research progress on the relationship between tumor cell adhesion molecules CD44, integrin, ICAM 1 and E-cadherin expression and chemoresistance.