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目的:了解非霍奇金淋巴瘤骨髓侵犯后与外周血液细胞之间的关系。方法:对95例NHL骨髓侵犯患者的骨髓涂片分类计数,记录其形态学改变,并对外周血液涂片进行分类。结果:549例NHL患者发生BMI或LMCL共95例,占17.3%,WBC<4.0×109/L11例,4.0×109/L≤WBC<10.0×109/L35例,WBC≥10.0×109/L49例。外周血分类正常:BMI占22.1%,LMCL占8.4%;外周血分类异常:BMI占6.3%,LMCL占63.2%。结论:BMI和LMCL在外周血中不一定呈白血病改变,对NHL患者不但要经常检测血象,更要定期监测患者的骨髓象,而且对LMCL的骨髓片应作化学染色,保证诊断的准确性。
Objective: To understand the relationship between non-Hodgkin’s lymphoma and peripheral blood cells after bone marrow invasion. Methods: The bone marrow smears of 95 patients with NHL bone marrow invasion were classified and counted. Morphological changes were recorded and the peripheral blood smears were classified. Results: There were 95 cases of BMI or LMCL in 549 cases of NHL, accounting for 17.3%, WBC <4.0 × 109 / L in 11 cases, 4.0 × 109 / L≤WBC <10.0 × 109 / L in 35 cases, WBC≥10 × 109 / L in 49 cases . Normal peripheral blood classification: BMI accounted for 22.1%, LMCL accounted for 8.4%; abnormal peripheral blood classification: BMI 6.3%, LMCL accounted for 63.2%. CONCLUSION: BMI and LMCL are not necessarily leukemia in peripheral blood. Not only the blood samples should be detected frequently in patients with NHL, but also the bone marrow of patients should be monitored regularly. The bone marrow slices of LMCL should be chemically stained to ensure the accuracy of diagnosis.