可生物降解长效注射给药系统具有局部注射给药一次后能持续几天甚至几个月释药的特点,日益受到生命科学研究者和临床医生的重视。本文介绍了长效注射给药系统的研发历程、生物降解聚合物的类型与特性以及该剂型的临床应用现况,同时客观评价了可生物降解注射剂的应用前景和存在问题。 Biodegradable long-acting injection delivery system with local injection administered once a few days or even months after the release of drug characteristics, increasingly by life science researchers and clinicians attention. This article describes the research and development history of long-acting injection delivery systems, the types and characteristics of biodegradable polymers and the clinical application of this dosage form. Meanwhile, the application prospects and existing problems of biodegradable injections are objectively evaluated.